John Markley
John L. Markley is an American biochemist.[1]
Markley focuses on NMR spectroscopy and its biological applications, structure function relationships in proteins, stable-isotope-assisted multinuclear magnetic resonance spectroscopy, processing and analysis of multi-dimensional NMR data; structural genomics and metabolomics.[2]
Marley is currently the Steenbock Professor of Biomolecular Structure at the University of Wisconsin–Madison and an Elected Fellow of the American Association for the Advancement of Science.[3][4]
Research publications[5][edit]
| 2020 | Dashti H, Westler WM, Wedell JR, Demler OV, Eghbalnia HR, Markley JL, Mora S. Probabilistic identification of saccharide moieties in biomolecules and their protein complexes. Scientific Data. 7: 210. PMID 32620933 DOI: 10.1038/s41597-020-0547-y |
| 2020 | Aceti DJ, Ahmed H, Westler WM, Wu C, Dashti H, Tonelli M, Eghbalnia H, Amarasinghe GK, Markley JL. Fragment screening targeting Ebola virus nucleoprotein C-terminal domain identifies lead candidates. Antiviral Research. 104822. PMID 32446802 DOI: 10.1016/j.antiviral.2020.104822 |
| 2020 | Alhajala HS, Markley JL, Kim JH, Al-Gizawiy MM, Schmainda KM, Kuo JS, Chitambar CR. The cytotoxicity of gallium maltolate in glioblastoma cells is enhanced by metformin through combined action on mitochondrial complex 1. Oncotarget. 11: 1531-1544. PMID 32391122 DOI: 10.18632/oncotarget.27567 |
| 2020 | Cai K, Frederick RO, Markley JL. 2mISCU interacts with NFU1, and ISCU[4Fe-4S] transfers its Fe-S cluster to NFU1 leading to the production of holo-NFU1. Journal of Structural Biology. 107491. PMID 32151725 DOI: 10.1016/j.jsb.2020.107491 |
| 2020 | Barnett BR, Fathi F, Falco Cobra P, Yi SY, Anderson JM, Eghbalnia HR, Markley JL, Yu JJ. Metabolic Changes in Synaptosomes in an Animal Model of Schizophrenia Revealed by H and H,C NMR Spectroscopy. Metabolites. 10. PMID 32102223 DOI: 10.3390/metabo10020079 |
| 2020 | Romero PR, Kobayashi N, Wedell JR, Baskaran K, Iwata T, Yokochi M, Maziuk D, Yao H, Fujiwara T, Kurusu G, Ulrich EL, Hoch JC, Markley JL. BioMagResBank (BMRB) as a Resource for Structural Biology. Methods in Molecular Biology. 2112: 187-218. PMID 32006287 DOI: 10.1007/978-1-0716-0270-6_14 |
| 2020 | Weber DK, Wang S, Markley JL, Veglia G, Lee W. PISA-SPARKY: an interactive SPARKY plugin to analyze oriented solid-state NMR spectra of helical membrane proteins. Bioinformatics. PMID 31930377 DOI: 10.1093/bioinformatics/btaa019 |
| 2020 | Tanrikulu IC, Westler WM, Ellison AJ, Markley JL, Raines RT. Templated Collagen "Double Helices" Maintain Their Structure. Journal of the American Chemical Society. PMID 31895554 DOI: 10.1021/jacs.9b07583 |
| 2020 | Lee W, Tonelli M, Frederick RO, Haruta M, Cornilescu G, Cornilescu CC, Sussman MR, Markley JL. Solution Structure Determination of Arabidopsis Thaliana RALF8 Illustrates the use of Cutting-Edge Software Developed at the National Magnetic Resonance Facility at Madison Biophysical Journal. 118: 62a. DOI: 10.1016/j.bpj.2019.11.514 |
| 2019 | Bortnov V, Tonelli M, Lee W, Lin Z, Annis DS, Demerdash ON, Bateman A, Mitchell JC, Ge Y, Markley JL, Mosher DF. Solution structure of human myeloid-derived growth factor suggests a conserved function in the endoplasmic reticulum. Nature Communications. 10: 5612. PMID 31819058 DOI: 10.1038/s41467-019-13577-5 |
References[edit]
- ^ "John Markley". Wisconsin Energy Institute. August 27, 2020.
- ^ "Scientist uses form to explain function of key building blocks of life". EurekAlert!. Retrieved 2020-08-27.
- ^ "John Markley". aaas.org. Retrieved May 14, 2017.
- ^ "John Markley". wisc.edu. Retrieved May 14, 2017.
- ^ "John L. Markley - Publications". Academic Tree. August 27, 2020.
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