4-Maleylacetoacetic acid
Appearance
Names | |
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Preferred IUPAC name
(2Z)-4,6-Dioxooct-2-enedioic acid | |
Other names
4-Maleylacetoacetate
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Identifiers | |
3D model (JSmol)
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ChEBI | |
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PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C8H8O6 | |
Molar mass | 200.146 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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4-Maleylacetoacetate (4-maleylacetoacetatic acid) is an intermediate in the metabolism of tyrosine. It is converted to fumarylacetoacetate by the enzyme 4-maleylacetoacetate cis-trans-isomerase. Gluthathione coenzymatically helps in conversion to fumarylacetoacetic acid.