OR5L2

OR5L2
Identifiers
Aliases	OR5L2, HSHTPCRX16, HTPCRX16, OR11-153, olfactory receptor family 5 subfamily L member 2
External IDs	MGI: 3030990; HomoloGene: 72031; GeneCards: OR5L2; OMA:OR5L2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q12.1 Start 55,827,219 bp End 55,828,154 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 D Start 87,777,397 bp End 87,783,444 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in amniotic fluid n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function signal transducer activity olfactory receptor activity G protein-coupled receptor activity odorant binding Cellular component plasma membrane membrane integral component of membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26338 258814 Ensembl ENSG00000205030 ENSMUSG00000075144 UniProt Q8NGL0 n/a RefSeq (mRNA) NM_001004739 NM_146817 RefSeq (protein) NP_001004739 n/a Location (UCSC) Chr 11: 55.83 – 55.83 Mb Chr 2: 87.78 – 87.78 Mb PubMed search
Wikidata
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Olfactory receptor 5L2 is a protein that in humans is encoded by the OR5L2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR5L2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.