List of Cash Box Best Sellers number-one singles of 1950
 | This article relies largely or entirely on a single source. (February 2023) |
These are the songs that reached number one on the Top 40 Best Sellers chart in 1950 as published by Cash Box magazine. Artists were not specified in the charts of this time period so songs may represent more than one version. The artist who most popularized each song is listed.
| Issue date | Song | Artist |
|---|---|---|
| January 7 | "I Can Dream, Can't I?" | The Andrews Sisters |
| January 14 | ||
| January 21 | ||
| January 28 | ||
| February 4 | ||
| February 11 | ||
| February 18 | "Dear Hearts and Gentle People" | Bing Crosby |
| February 25 | "Chattanoogie Shoe Shine Boy" | Red Foley |
| March 4 | ||
| March 11 | ||
| March 18 | ||
| March 25 | "Music! Music! Music!" | Teresa Brewer |
| April 1 | ||
| April 8 | ||
| April 15 | ||
| April 22 | "The Third Man Theme" | Anton Karas |
| April 29 | ||
| May 6 | ||
| May 13 | ||
| May 20 | ||
| May 27 | ||
| June 3 | ||
| June 10 | ||
| June 17 | ||
| June 24 | ||
| July 1 | ||
| July 8 | "Bewitched, Bothered and Bewildered" | Vivienne Segal |
| July 15 | ||
| July 22 | ||
| July 29 | ||
| August 5 | "Mona Lisa" | Nat King Cole |
| August 12 | ||
| August 19 | ||
| August 26 | ||
| September 2 | "Goodnight, Irene" | Gordon Jenkins and The Weavers |
| September 9 | ||
| September 16 | ||
| September 23 | ||
| September 30 | ||
| October 7 | ||
| October 14 | ||
| October 21 | ||
| October 28 | ||
| November 4 | ||
| November 11 | "Harbor Lights" | Sammy Kaye |
| November 18 | ||
| November 25 | ||
| December 2 | ||
| December 9 | ||
| December 16 | "The Thing" | Phil Harris |
| December 23 | "Harbor Lights" | Sammy Kaye |
| December 30 | "Tennessee Waltz" | Patti Page |