OR4F15

OR4F15
Identifiers
Aliases	OR4F15, olfactory receptor family 4 subfamily F member 15
External IDs	MGI: 3031143; HomoloGene: 74054; GeneCards: OR4F15; OMA:OR4F15 - orthologs
Gene location (Human) Chr. Chromosome 15 (human) Band 15q26.3 Start 101,812,202 bp End 101,820,197 bp
Gene location (Mouse) Chr. Chromosome 2 (mouse) Band 2|2 E3 Start 111,810,202 bp End 111,820,626 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in lung multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390649 258439 Ensembl ENSG00000182854 ENSMUSG00000109528 UniProt Q8NGB8 n/a RefSeq (mRNA) NM_001001674 NM_146447 RefSeq (protein) NP_001001674 n/a Location (UCSC) Chr 15: 101.81 – 101.82 Mb Chr 2: 111.81 – 111.82 Mb PubMed search
Wikidata
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Olfactory receptor 4F15 is a protein that in humans is encoded by the OR4F15 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Gilad Y, Bustamante CD, Lancet D, Pääbo S (2003). "Natural selection on the olfactory receptor gene family in humans and chimpanzees". Am. J. Hum. Genet. 73 (3): 489–501. doi:10.1086/378132. PMC 1180675. PMID 12908129.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR4F15+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.