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Danielle Bassett

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For other people with the same name, see Danielle Smith (disambiguation).
Dani Bassett
Bornc. 1981
NationalityAmerican
Alma materPennsylvania State University (BS)
University of Cambridge (PgCert, PhD)
SpouseLee Bassett (m. 2006-2021) [1]
ChildrenTwo sons, b. 2011 and 2014 [1]
AwardsSloan Research Fellowship
MacArthur fellowship
Erdős–Rényi Prize
ONR Young Investigator
Scientific career
Fieldsphysics, neuroscience
InstitutionsUniversity of California, Santa Barbara
University of Pennsylvania
Doctoral advisorThomas Duke, Edward T. Bullmore, Andreas Meyer-Lindenberg
Websitewww.danisbassett.com

Dani Smith Bassett (born c. 1981[2]) is an American physicist and systems neuroscientist who was the youngest individual to be awarded a 2014 MacArthur fellowship.[3][4]

Bassett, whose pronouns are they/them,[5][6] was also awarded a 2014 Sloan fellowship.[7] They are currently the J. Peter Skirkanich Professor in the Departments of Bioengineering, Electrical & Systems Engineering, Physics & Astronomy, Neurology, and Psychiatry at the University of Pennsylvania[2][8][9][10] and an external professor of the Santa Fe Institute.[11] Their work focuses on applying network science to the study of learning in the human brain[2] in addition to the study of other complex physical and biological systems.[8]

Early life and education

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Dani S. Bassett (born Danielle Perry) was born in 1981 and was raised in Lock Haven and Reading, Pennsylvania.[12] Pursuing a passion for medicine, and following in family footsteps, Bassett began higher education in an RN program at the Reading Hospital School of Nursing. After discovering a passion for mathematics, Bassett sought to combine the concepts of physics and mathematics to neuroscience. Bassett graduated from Pennsylvania State University with a bachelor of science in physics in 2004.[3] Basset received the NIH-Cambridge Scholarship and the Winston Churchill Scholarship and studied at the University of Cambridge. Bassett received a certificate in postgraduate studies from Churchill College, Cambridge in 2005 and a doctor of philosophy from King's College, Cambridge in 2009.[13]

Career

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Dani S. Bassett became a postdoctoral associate from 2009 to 2011 at the University of California, Santa Barbara and a Sage Junior Research Fellow from 2011 to 2013. Bassett is currently on the faculty of the University of Pennsylvania as the J. Peter Skirkanich Professor in the department of bioengineering.[3]

Bassett's early work used and developed concepts in network science and complex systems to understand the organization of the brain.[3] Bassett focused on the "small-world" topology of the brain, which refers to networks and the way in which they express dense local clustering and how the presence of connections leads to a short path of communication between distant nodes. Bassett's research team applied mathematical concepts in graph theory to small-world analysis to quantify cortical connectivity. The small-world models Bassett produced introduced a means to understanding the brain's structure and function.[14]

These topological measures developed early in Bassett's career were used to examine the cortex and its divisions and wiring to determine the properties that the cortex has. Bassett found that of the various cortical regions, the multimodal portion of the cortex has hierarchical organizations with low clustering, and the transmodal portion was more assortative. Bassett applied these concepts to schizophrenic individuals and noticed that the organization of these portions were abnormal with increasing connection distances. Bassett continues to research the implications of network behaviors on mental disorders, particularly schizophrenia.[15]

Bassett also has worked with Fabio Pasqualetti (currently at University of California, Riverside) to apply control theory to the study of the brain;[16] their initial study on the subject was published in 2015.[17]

Bassett and their team have also been conducting research regarding brain flexibility. Brain flexibility is how often a region of the brain switches communication patterns. The more often the brain switches patterns, the more flexible the brain is. They have also found correlations between the ability for the brain to learn and the flexibility of the brain. Bassett's research may have implications in rehabilitation, particularly in patients who have had a stroke.[18]

Research

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Bassett's research at the University of Pennsylvania explores a wide range of questions related to brain function and learning.[19] They investigate how the brain navigates written text, the influence of brain structure on social networks and behavior, and the prediction of disease progression based on brain connectivity patterns.[20] Additionally, Bassett explores the optimization of learning by utilizing network representations of both the brain and learning materials.

Bassett's work has been met with both praise and skepticism within the neuroscience community.[21] While some view their application of network science as a promising avenue for understanding the brain's higher-order organization, others question the validity of their findings and their potential clinical applications.[22]

Awards and honors

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During their undergraduate studies, Bassett was the sole recipient of the Paul Axt Prize, which is given to a student who demonstrates commitment to inquiry and fosters intellectual curiosity. They were also a Schreyer Honors Scholar and were named the Most Achieving Undergraduate Woman of the Year in 2004. Bassett received the Winston Churchill Scholarship and the National Institute of Health- Cambridge Health Science Scholarship to fund their graduate education. Bassett received the Alumni Achievement Award from the Schreyer Honors College at Pennsylvania State University for extraordinary accomplishment under 35 years of age. Bassett was named American Psychological Society "Rising Star" in December 2012. In January 2014, they won the Sloan Research Fellowship.[13] Most notably, they were one of the 21 winners of the MacArthur Research Fellowship in September 2014.[3]

In 2016, Bassett was named one of the ten most brilliant scientists of the year by Popular Science magazine.[23] In 2017, they received the Lagrange Prize in Complex Systems.[24] In 2018, Bassett received the Erdős–Rényi Prize for "fundamental contributions to our understanding of the network architecture of the human brain".[25]

Bassett was named a fellow of the American Institute for Medical and Biological Engineering in 2020[26] and a fellow of the American Physical Society in 2021.[27]

Personal life

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Dani S. Bassett has two children. During Bassett's earlier years, they enjoyed captaining the crew team at King's College, Cambridge.[1] Bassett's twin is Perry Zurn, professor at the department of philosophy at American University.[28]

Selected publications

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Books

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  • Curious Minds: The Power of Connection (2022) : Cambridge: The MIT Press . (ISBN 0262047039)

Articles

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References

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  1. ^ a b c "Personal". Complex Systems Group. Archived from the original on 2017-12-31. Retrieved 2015-11-21.
  2. ^ a b c Avril, Tom (September 16, 2014). "Penn researcher Danielle Bassett wins a 'genius grant'". Philadelphia Media Network. Archived from the original on 10 October 2014. Retrieved 17 September 2014.
  3. ^ a b c d e "Danielle Bassett". MacArthur Foundation. Retrieved 17 September 2014.
  4. ^ Lee, Felicia R. (September 17, 2014). "MacArthur Awards Go to 21 Diverse Fellows". The New York Times. Retrieved 17 September 2014.
  5. ^ "Personal". Complex Systems Lab UPenn. Retrieved 2022-01-27.
  6. ^ "NIH VideoCast - Thinking Critically About How We Do Science". videocast.nih.gov. 5 January 2022. Retrieved 2022-01-27.
  7. ^ "2014 Sloan Research Fellows". Alfred P. Sloan Foundation. Archived from the original on 6 October 2014. Retrieved 17 September 2014.
  8. ^ a b "Penn Engineering – Research Directory Profile". University of Pennsylvania. Retrieved 17 September 2014.
  9. ^ "Dani S. Bassett". Retrieved 2022-01-27.
  10. ^ "Bassett's CV as of 9/2021" (PDF). January 27, 2022.
  11. ^ "People | Santa Fe Institute". www.santafe.edu. Archived from the original on 2022-05-25. Retrieved 2022-01-27.
  12. ^ Hagan, Molly (June 2015). "Danielle Bassett". Current Biography. 76 (6): 7–11.
  13. ^ a b "Danielle Bassett" (PDF). Retrieved 19 November 2015.
  14. ^ Bassett, D. S.; Bullmore, E. (1 December 2006). "Small-World Brain Networks". The Neuroscientist. 12 (6): 512–523. CiteSeerX 10.1.1.132.2709. doi:10.1177/1073858406293182. PMID 17079517. S2CID 4305469.
  15. ^ Bassett, D. S.; Bullmore, E.; Verchinski, B. A.; Mattay, V. S.; Weinberger, D. R.; Meyer-Lindenberg, A. (10 September 2008). "Hierarchical Organization of Human Cortical Networks in Health and Schizophrenia". Journal of Neuroscience. 28 (37): 9239–9248. doi:10.1523/JNEUROSCI.1929-08.2008. PMC 2878961. PMID 18784304.
  16. ^ Servick, Kelly (2019-04-12). "The trespasser". Science. 364 (6436): 118–121. Bibcode:2019Sci...364..118S. doi:10.1126/science.364.6436.118. ISSN 0036-8075. PMID 30975871. S2CID 109939235.
  17. ^ Bassett, Danielle S.; Grafton, Scott T.; Miller, Michael B.; Vettel, Jean M.; Medaglia, John D.; Kahn, Ari E.; Yu, Alfred B.; Telesford, Qawi K.; Cieslak, Matthew (2015-10-01). "Controllability of structural brain networks". Nature Communications. 6: 8414. arXiv:1406.5197. Bibcode:2015NatCo...6.8414G. doi:10.1038/ncomms9414. ISSN 2041-1723. PMC 4600713. PMID 26423222.
  18. ^ "Danielle Bassett: The Flexible Brain". BrainFacts.
  19. ^ Servick, Kelly. "This physicist is trying to make sense of the brain's tangled networks". Science.org.
  20. ^ Lerner, Evan (30 January 2019). "Danielle Bassett on Understanding Knowledge Networks in the Brain". Penn Engineering Blog.
  21. ^ Tait, Amelia (4 September 2022). "Are you a busybody, a hunter or a dancer? A new book about curiosity reveals all". The Observer.
  22. ^ Garnett, Carla (4 March 2022). "Bassett Considers 'Beautiful, Rational Process of Science'". NIH Record.
  23. ^ Greenwood, Veronique; Willyard, Cassandra (September 13, 2016). "The Woman Who Reimagines How The Brain Works Danielle Bassett is one of the 10 most brilliant people of 2016". Popular Science. Retrieved 28 April 2017.
  24. ^ "Prize". www.isi.it. Retrieved 2022-01-27.
  25. ^ "Erdős-Rényi Prize for Danielle Bassett". 2018-06-14.
  26. ^ "Danielle Bassett Named American Institute for Medical and Biological Engineering (AIMBE) Fellow". Penn Institute for Computational Science, University of Pennsylvania. April 13, 2020. Retrieved 2021-10-13.
  27. ^ "APS Fellow Archive". Retrieved 2021-10-13.
  28. ^ "Danielle Bassett / Personal". Retrieved 27 November 2018.
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