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Paul Brindley (biologist)

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Paul Brindley
Born1954
Brisbane, Australia
NationalityAustralian
Alma materUniversity of Queensland
SpouseVictoria Mann
ChildrenMeredith Brindley
Scientific career
FieldsHelminthology, Tropical Medicine
InstitutionsGeorge Washington University, QIMR Berghofer Medical Research Institute, Tulane University, University College Dublin

Paul J Brindley (born 1954) is an Australian parasitologist, microbiologist, and helminthologist. He is professor of Microbiology, Immunology, and Tropical Medicine at the George Washington University.[1]

Education & Career

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Paul Brindley received a doctorate from the University of Queensland, Brisbane, Australia and completed postdoctoral training at the NIAID's Laboratory of Parasitic Diseases, National Institutes of Health, Bethesda, Maryland.

He has held faculty level appointments at the QIMR Berghofer Medical Research Institute, Brisbane, Australia, University College Dublin, Ireland, and Tulane University, New Orleans, Louisiana, where he was the William Vincent Professor of Tropical Medicine. He was the recipient of the Scholar Award in Molecular Parasitology, Infectious Diseases Research of the Burroughs Wellcome Fund (2001-2006), and is a Fellow of the American Society of Tropical Medicine and Hygiene.[2] He is co-Editor-in-Chief of PLOS Neglected Tropical Diseases.[3]

His current research focuses on neglected tropical diseases (NTDs) and NTD associated cancers. He is pursuing functional genomics and other approaches to characterize new disease interventions. Brindley and co-investigators reported the activity of CRISPR-Cas programmed editing of the human blood fluke, Schistosoma mansoni[4] and the human liver fluke, Opisthorchis viverrini.[5]

In December 2019, he was awarded by Khon Kaen University, Thailand a Doctorate of Science, honoris causa.[6]

References

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  1. ^ "Paul Brindley". www.gwumc.edu. Retrieved 1 April 2018.
  2. ^ "Loop Paul Brindley". loop.frontiersin.org. Retrieved 1 April 2018.
  3. ^ "PLOS Neglected Tropical Diseases Editors-in-Chief". journals.plos.org. Retrieved 22 July 2020.
  4. ^ Ittiprasert, Wannaporn; Mann, Victoria H.; Karinshak, Shannon E.; Coghlan, Avril; Rinaldi, Gabriel; Sankaranarayanan, Geetha; Chaidee, Apisit; Tanno, Toshihiko; Kumkhaek, Chutima; Prangtaworn, Pannathee; Mentink-Kane, Margaret M.; Cochran, Christina J.; Driguez, Patrick; Holroyd, Nancy; Tracey, Alan; Rodpai, Rutchanee; Everts, Bart; Hokke, Cornelis H.; Hoffmann, Karl F.; Berriman, Matthew; Brindley, Paul J. (2019). "Programmed genome editing of the omega-1 ribonuclease of the blood fluke, Schistosoma mansoni". eLife. 8. doi:10.7554/eLife.41337. PMC 6355194. PMID 30644357.
  5. ^ Arunsan, Patpicha; Ittiprasert, Wannaporn; Smout, Michael J.; Cochran, Christina J.; Mann, Victoria H.; Chaiyadet, Sujittra; Karinshak, Shannon E.; Sripa, Banchob; Young, Neil David; Sotillo, Javier; Loukas, Alex; Brindley, Paul J.; Laha, Thewarach (2019). "Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity". eLife. 8. doi:10.7554/eLife.41463. PMC 6355195. PMID 30644359.
  6. ^ "KKU grants Honorary Doctorate Degrees and honorary awards 2019". kku.ac.th. 7 December 2019. Retrieved 22 July 2020.