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Daniel Alagille

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Daniel Alagille
Born(1925-01-24)24 January 1925
Paris
Died8 November 2005(2005-11-08) (aged 80)
NationalityFrench
Known forAlagille syndrome
Scientific career
FieldsPediatrics, hepatology
InstitutionsBicêtre Hospital

Daniel Alagille (24 January 1925 – 8 November 2005) was a French physician who specialized in pediatric hepatology, the study of childhood liver diseases.

Biography[edit]

Alagille was born in Paris in 1925. He was educated at the University of Paris and then worked at the University of Paris-Sud, becoming a full professor in 1971.[1]

Alagille directed a pediatric hepatology unit at Bicêtre Hospital in Paris for many years before retiring in 1990.[2] Alagille syndrome is named for him,[3] as he had first described the condition in 1969.[4] He recognized that a number of his patients with bile duct problems also suffered from problems in other body parts, including the heart and face. Alagille established the initial criteria for diagnosing the syndrome.[5]

Alagille served as editor-in-chief of the Revue internationale d'hépatologie and the Archives francaises de pédiatrie. He was received into the French National Order of Merit in 1967 and the Legion of Honour in 1988.[1] With his former trainee and colleague Michel Odièvre, he wrote the first textbook of pediatric hepatology, Maladies du Foie et des Voies Biliaires chez l'Enfant (Liver and Bile Duct Diseases in Children).[2] In 1994, he became the third recipient of the Andrew Sass Kortsak Award from the Canadian Liver Foundation.[6]

Alagille died in 2005 following heart surgery.[2]

References[edit]

  1. ^ Jump up to: a b Beighton, Peter; Beighton, Greta (1997). The Person Behind the Syndrome. Springer Science & Business Media. pp. 535–. ISBN 978-1-4471-0925-9. Retrieved February 12, 2015.
  2. ^ Jump up to: a b c Roy, Claude; Alvarez, Fernando; Grand, Richard (February 2006). "Obituary for Daniel Alagille". Journal of Pediatric Gastroenterology and Nutrition. 42 (2): 127–128. doi:10.1097/01.mpg.0000189357.93784.48.
  3. ^ Kelly, Evelyn (2013). Encyclopedia of Human Genetics and Disease. ABC-CLIO. p. 57. ISBN 978-0313387142. Retrieved February 12, 2015.
  4. ^ Yucel, H; Hoorntje, S; Bravenboer, B (January 2010). "Renal abnormalities in a family with Alagille syndrome". The Netherlands Journal of Medicine. 68 (1): 38–39. PMID 20103821. Retrieved February 12, 2015.
  5. ^ Murray, Karen F.; Horslen, Simon (11 December 2013). Diseases of the Liver in Children: Evaluation and Management. Springer Science & Business Media. pp. 227–. ISBN 978-1-4614-9005-0. Retrieved February 12, 2015.
  6. ^ "Andrew Sass Kortsak Award". Canadian Liver Foundation. Retrieved February 12, 2015.
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