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Presqualene diphosphate synthase

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Presqualene diphosphate synthase
Identifiers
EC no.2.5.1.103
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
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NCBIproteins

Presqualene diphosphate synthase (EC 2.5.1.103, SSL-1 (gene)) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate:(2E,6E)-farnesyl-diphosphate farnesyltransferase (presqualene diphosphate forming).[1] This enzyme catalyses the following chemical reaction

2 (2E,6E)-farnesyl diphosphate presqualene diphosphate + diphosphate

This enzyme is isolated from the green alga Botryococcus braunii BOT22.

References

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  1. ^ Niehaus TD, Okada S, Devarenne TP, Watt DS, Sviripa V, Chappell J (2011). "Identification of unique mechanisms for triterpene biosynthesis in Botryococcus braunii". Proc. Natl. Acad. Sci. USA. 108 (30): 12260–12265. Bibcode:2011PNAS..10812260N. doi:10.1073/pnas.1106222108. PMC 3145686. PMID 21746901.
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