OR2T33

OR2T33
Identifiers
Aliases	OR2T33, OR1-56, olfactory receptor family 2 subfamily T member 33, OR2T32
External IDs	MGI: 3030148; HomoloGene: 88349; GeneCards: OR2T33; OMA:OR2T33 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) Band 1q44 Start 248,269,917 bp End 248,277,976 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B1.3 Start 58,673,778 bp End 58,679,594 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle gonad monocyte bone marrow blood left lobe of thyroid gland smooth muscle tissue prefrontal cortex right lobe of thyroid gland primary visual cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 391195 257917 Ensembl ENSG00000177212 ENSMUSG00000059504 UniProt Q8NG76 Q7TRZ7 RefSeq (mRNA) NM_001004695 NM_001011760 RefSeq (protein) NP_001004695 NP_001011760 Location (UCSC) Chr 1: 248.27 – 248.28 Mb Chr 11: 58.67 – 58.68 Mb PubMed search
Wikidata
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Olfactory receptor 2T33 is a protein that in humans is encoded by the OR2T33 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi:10.1038/nature04727. PMID 16710414.

External links

• OR2T33+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.