PHF3

PHF3
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2DME
Identifiers
Aliases	PHF3, PHD finger protein 3
External IDs	OMIM: 607789; MGI: 2446126; HomoloGene: 9040; GeneCards: PHF3; OMA:PHF3 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	63,779,336 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	30,913,002 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; Achilles tendon; ; germinal epithelium; ; tibia; ; endothelial cell; ; parietal pleura; ; internal globus pallidus; ; visceral pleura; ; corpus callosum; ; palpebral conjunctiva;
	Top expressed in
	secondary oocyte; ; zygote; ; tail of embryo; ; primary oocyte; ; genital tubercle; ; neural layer of retina; ; renal corpuscle; ; left lung lobe; ; cumulus cell; ; mesenteric lymph nodes;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; molecular function;
Cellular component	cellular component;
Biological process	multicellular organism development; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	23469
	213109
	ENSG00000118482
	ENSMUSG00000048874
	Q92576
	n/a
NM_001290259; NM_001290260; NM_015153; NM_001370348; NM_001370349;
	NM_001370350
	NM_001081080; NM_025871
NP_001277188; NP_001277189; NP_055968; NP_001357277; NP_001357278;
	NP_001357279
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

PHD finger protein 3 is a protein that in humans is encoded by the PHF3 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118482 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000048874 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Fischer U, Struss AK, Hemmer D, Michel A, Henn W, Steudel WI, Meese E (Mar 2002). "PHF3 expression is frequently reduced in glioma". Cytogenet Cell Genet. 94 (3–4): 131–6. doi:10.1159/000048804 (inactive 2024-07-25). PMID 11856869. S2CID 44396216.{{cite journal}}: CS1 maint: DOI inactive as of July 2024 (link)
^ "Entrez Gene: PHF3 PHD finger protein 3".

Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
Nagase T, Seki N, Ishikawa K, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Res. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID 9039502.
Struss AK, Romeike BF, Munnia A, et al. (2001). "PHF3-specific antibody responses in over 60% of patients with glioblastoma multiforme". Oncogene. 20 (31): 4107–14. doi:10.1038/sj.onc.1204552. PMID 11464277.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi:10.1038/nature02055. PMID 14574404.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Ballif BA, Villén J, Beausoleil SA, et al. (2005). "Phosphoproteomic analysis of the developing mouse brain". Mol. Cell. Proteomics. 3 (11): 1093–101. doi:10.1074/mcp.M400085-MCP200. PMID 15345747.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Pallasch CP, Struss AK, Munnia A, et al. (2005). "Autoantibodies against GLEA2 and PHF3 in glioblastoma: tumor-associated autoantibodies correlated with prolonged survival". Int. J. Cancer. 117 (3): 456–9. doi:10.1002/ijc.20929. PMID 15906353. S2CID 32083805.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

External links

PHF3+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 6 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000118482 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000048874 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid11856869-5] Fischer U, Struss AK, Hemmer D, Michel A, Henn W, Steudel WI, Meese E (Mar 2002). "PHF3 expression is frequently reduced in glioma". Cytogenet Cell Genet. 94 (3–4): 131–6. doi:10.1159/000048804 (inactive 2024-07-25). PMID 11856869. S2CID 44396216.{{cite journal}}: CS1 maint: DOI inactive as of July 2024 (link)

[entrez-6] "Entrez Gene: PHF3 PHD finger protein 3".

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References

Further reading

External links