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Fikri Alican

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Fikri Alican
Fikri Alican (age 26) in May 1955
Born(1929-04-02)2 April 1929
Adapazarı, Sakarya, Turkey
Died19 August 2015(2015-08-19) (aged 86)
Istanbul, Turkey
Resting placeAdapazarı, Sakarya, Turkey
NationalityTurkish
EducationRobert College (B.S., 1949)
Istanbul University (M.D., 1955)
University of Mississippi (M.S., 1962)
Known forLaboratory and clinical research in the transplantation of the liver, lungs, and small intestines; studies in physiology, most notably in transplantation biology and in the physiology of shock
SpouseHalide Alican (1960–2015, his death)
Children
  • Necip Fikri Alican
  • Fuat Varol Alican
Scientific career
FieldsMedicine, physiology, general surgery, organ transplantation
InstitutionsIstanbul University
University of Mississippi

Fikri Alican (2 April 1929 – 19 August 2015) was a Turkish scientist and physician with various contributions to medical science, ranging from organ transplantation to physiology.[a]

Early life and career[edit]

Alican was born in Adapazarı, a city in northwestern Turkey, 150 km east of Istanbul. He left his hometown after middle school, attending high school and college in Istanbul, where he graduated from Robert College with a B.S. (1949) and from Istanbul University with an M.D. (1955).[b][1] He did his residency at the Istanbul University Medical Center's Clinic of Treatment and Exploratory Surgery, also known as Surgical Clinic #4, headed by Şinasi Hakkı Erel.[2] It is there that he met his future wife, Halide Ihlamur, later Halide Alican, a surgical nurse working at the same clinic.[3]

After completing his residency in general surgery at Istanbul University, his growing interest in the field of organ transplantation, then in its heyday, took him to Jackson, Mississippi, where he joined the University of Mississippi team leading the world in transplantation research, including the first lung transplant (11 June 1963) and the first heart transplant (23 January 1964), under the leadership of James D. Hardy.[c][4] A few weeks after his arrival there in the summer of 1960, he proposed to Ihlamur, as he always called her, even after she took his name and dropped hers, and they got married in Jackson in November 1960, remaining married for fifty-five years (1960–2015) until his death at age eighty-six.[5] He also obtained a master's degree (M.S., 1962) in physiology at the University of Mississippi, studying with Arthur C. Guyton, while working as a research fellow (soon to become a research associate) in Hardy's department of surgery.[6]

Best known for his work in organ transplantation, though with some notable initiatives in physiology as well, Alican later established a successful private practice as a general surgeon. His professional career was divided between medical research in the United States and private practice in Turkey.

Main Contributions[edit]

Alican's main contributions came in the 1960s (1960–1971) when he worked at the University of Mississippi Medical Center (UMMC) in the pioneering days of laboratory research and clinical studies in organ transplantation.[7][8] His research focused largely on the lungs[9][10][11][12][13][14][15][16][17][18][19] and on the liver,[20][21][22][23][24][25][26][27] though he is also known for his work on intestinal transplantation.[28] He performed the first ever simultaneous bilateral lung transplantation in canines, one of many such operations paving the way for the procedure in humans.[15][16][17][18][19]

His role in the development of surgical techniques in transplantation was complemented by his work in physiology,[29][30][31][32][33] including transplantation biology in general[34] as well as a particular specialty in the physiology of shock.[35][36][37][38]

Relocating to Istanbul in 1971, he held a professorship in surgery at Istanbul University until 1979, turning to private practice upon the institution of legal and regulatory changes barring academic physicians from working outside the university.[39] At the time of his departure from the University of Mississippi, he was an attending surgeon at the university hospital as well as associate director of the transplantation program there.[40] Twenty years later, he became a founding member ("fellow") of the James D. Hardy Society[permanent dead link], established in 1991.[41][42]

He has published extensively both in English and in Turkish. His journal articles, mostly in English, are almost exclusively in the areas of organ transplantation and physiology. His monographs, all in Turkish, are more diverse, ranging from general surgery to organ transplantation to cancer research and the in-depth study of various other diseases. The division mirrors the transformation of his career from medical research in the United States to general surgery in Turkey.

His autobiography (2000/2007) describes that transformation as coming with a natural obstacle to research: the relative scarcity of institutional resources in Turkey at that time.[43] He notes that this not only held back progress in laboratory and clinical studies but also impeded scholarly initiatives inevitably undermined by the inadequacy of academic libraries. The solution he reports having implemented is the creation and maintenance of his own library, complete with a card catalog, populated with entries from leading medical journals acquired with his own funds.[44] Specifically, he reports having maintained personal subscriptions to twenty-two medical journals for over thirty years.[d] He identifies these periodical holdings, supplemented by the selective acquisition of books on an ongoing but less regular schedule, as the main flow of information for the wall-to-wall card catalog in his office where he would personally enter the bibliographic details of each article in every issue. Alican credits this makeshift system for enabling him to publish a combined total of 3,000 pages on top of his output in the United States.[e][47]

Selected publications[edit]

Books[edit]

Date Publication
1960 Alican, Fikri (1960). Anesteziyoloji: Ameliyata Hazırlık, Ameliyat, Ameliyat Sonrası [Anesthesiology: Preoperative Preparation, Surgery, Postoperative Care]. 750 Yataklı Çamlıca Askeri Göğüs Hastalıkları Hastenesi Yayınları No. 2. Istanbul: 750 Yataklı Çamlıca Askeri Göğüs Hastalıkları Hastenesi.
1968 Alican, Fikri (1968). Ameliyata Hazırlık, Anestezi, Ameliyat Sonrası Bakımı [Preoperative Preparation, Anesthesia, Postoperative Care]. Istanbul: Kasımpaşa Deniz Hastanesi Yayınevi.[f]
1968 Alican, Fikri (1968). Transplantasyon Biyolojisi: Hızla Gelişmekte Olan Yeni Bir Bilim [Transplantation Biology: A Rapidly Developing New Science]. Istanbul: İstanbul Üniversitesi Tıp Fakültesi.
1981 Alican, Fikri (1981). Meme Kanseri [Breast Cancer]. Istanbul: Avrupa Tıp Kitapçılık.
1993 Alican, Fikri (1993). Kanser [Cancer]. Istanbul: Avrupa Tıp Kitapçılık. Second, enlarged and updated edition, 1997.
1993 Alican, Fikri (1993). Meme Hastalıkları [Diseases of the Breast]. Istanbul: Avrupa Tıp Kitapçılık.
1993 Alican, Fikri (1993). Transplantasyon [Transplantation]. Istanbul: Avrupa Tıp Kitapçılık.
1994–1995 Alican, Fikri (1994–1995). Cerrahi Dersleri [Lectures in Surgery]. Vol. Three volumes. Istanbul: Dünya Tıp Kitabevi.
1996 Alican, Fikri (1996). Meme Kanseri: Değişen Kavramlar ve Güncel Tedaviler [Breast Cancer: Changing Conceptions and Current Treatments]. Istanbul: Avrupa Tıp Kitapçılık.
2000 Alican, Fikri (2000). Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak]. Istanbul: Doğan Kitap. ISBN 978-9-7567-7047-4. Second, revised and enlarged edition with pictures published by Nobel Tıp Kitabevleri, 2007. ISBN 978-9-7542-0574-9 [Autobiography.]
2007 Alican, Fikri (2007). Genel Cerrahi [General Surgery]. Vol. Two volumes. Istanbul: Nobel Tıp Kitabevleri. ISBN 978-9-7542-0532-9 (vol. 1). ISBN 978-9-7542-0533-6 (vol. 2). [Compilation of the author's previous books on medicine.][g]

Articles[edit]

Date Publication
1961 Alican, Fikri; Hardy, James D. (December 1961). "Mechanisms of Shock as Reflected in Studies of Lymph of Abdominal Organs". Surgery, Gynecology & Obstetrics [later: Journal of the American College of Surgeons]. 113: 743–756. ISSN 0039-6087. PMID 13860423.
1961 Alican, Fikri; Hardy, James D. (1961). "Relationship and Significance of the Levels of Direct Bilirubin, Indirect Bilirubin, and Alkaline Phosphatase in Lymph, Blood, and Urine After Ligation of the Common Bile Duct". Surgical Forum. 12: 337–339. ISSN 0071-8041. PMID 13860424.
1961 Hardy, James D.; Alican, Fikri (July 1961). "Ischemic Gangrene without Major Organic Vascular Occlusion: An Enlarging Concept". Surgery. 50 (1): 107–114. ISSN 0039-6060. PMID 13711520.
1962 Alican, Fikri (March 1962). "A Sensitive Method for Recording Lymph Flow: Observations on the Dynamics of Hepatosplanchnic Blood and Lymph". The Journal of Surgical Research. 2 (2): 104–109. doi:10.1016/S0022-4804(62)80004-3. ISSN 0022-4804. PMID 13860425.
1962 Alican, Fikri (August 1962). "Pathophysiology of Endotoxin Shock: Clinical Observations and Experimental Studies". The American Journal of the Medical Sciences. 244 (2): 237–257. doi:10.1097/00000441-196208000-00014. ISSN 0002-9629. PMID 13860426.
1962 Alican, Fikri; Hardy, James D. (August 1962). "Lymphatic Transport of Bile Pigments and Alkaline Phosphatase in Experimental Common Duct Obstruction". Surgery. 52 (2): 366–372. ISSN 0039-6060. PMID 13860422.
1962 Alican, Fikri; Hardy, James D. (1962). "Sympatho-Adrenal System in Endotoxin Shock". Surgical Forum. 13: 8–10. ISSN 0071-8041. PMID 14012021.
1962 Alican, Fikri; Dalton, Jr., Martin L.; Hardy, James D. (June 1962). "Experimental Endotoxin Shock: Circulatory Changes with Emphasis upon Cardiac Function". The American Journal of Surgery. 103 (6): 702–708. doi:10.1016/0002-9610(62)90249-0. ISSN 0002-9610. PMID 13860421.
1963 Alican, Fikri; Hardy, James D. (9 March 1963). "Lung Reimplantation: Effect on Respiratory Pattern and Function". JAMA. 183 (10): 849–853. doi:10.1001/jama.1963.63700100001013. ISSN 0098-7484. PMID 14012020.
1963 Hardy, James D.; Eraslan, Şadan; Dalton, Jr., Martin L.; Alican, Fikri; Turner, Manson Don (May 1963). "Re-Implantation and Homotransplantation of the Lung: Laboratory Studies and Clinical Potential". Annals of Surgery. 157 (5): 707–718. doi:10.1097/00000658-196305000-00005. ISSN 0003-4932. PMC 1466537. PMID 13960767.
1966 Hardy, James D.; Alican, Fikri (1966). "Lung Transplantation". Advances in Surgery. 2: 235–264. ISSN 0065-3411. PMID 5333296.
1967 Alican, Fikri (1967). "Experimental Orthotopic Liver Transplantation: Experience with 150 Dogs". New Istanbul Contribution to Clinical Science. 9 (3): 71–98. ISSN 0028-5447. PMID 16300153.
1967 Alican, Fikri (April 1967). "Köpekte Total Hepatektomiden Sonra Karaciğerin Tekrar Yerine Takılması [Replantation of the Liver in Dogs Following Total Hepatectomy]". Türk Tıp Cemiyeti Mecmuası. 33 (4): 209–226. ISSN 0494-2736. PMID 4863470.
1967 Alican, Fikri (May 1967). "Eksperimantal Karaciğer Homotransplantasyonu [Experimental Liver Homotransplantation]". Türk Tıp Cemiyeti Mecmuası. 33 (5): 296–311. ISSN 0494-2736.
1967 Alican, Fikri; Hardy, James D. (June 1967). "Eksperimantal Akciğer Transplantasyonu: Teknik, Fizyolojik ve İmmünolojik Problemler [Experimental Lung Transplantation: Technical, Physiological and Immunological Problems]". Türk Tıp Cemiyeti Mecmuası. 33 (6): 319–329. ISSN 0494-2736. PMID 4865363.
1967 Alican, Fikri; Hardy, James D. (August 1967). "Replantation of the Liver in Dogs". The Journal of Surgical Research. 7 (8): 368–375. doi:10.1016/0022-4804(67)90080-7. ISSN 0022-4804.
1969 Alican, Fikri; Hardy, James D. (1969). "A Description of the Course of Long-Term Survivors of Dog Liver Replantation". Surgical Forum. 20: 365–367. ISSN 0071-8041. PMID 4910609.
1970 Alican, Fikri (December 1970). "The Present Status of Lung Transplantation". Journal of the Tennessee Medical Association [later: Tennessee Medicine]. 63 (12): 1011–1021. ISSN 0040-3318. PMID 5532334.
1970 Alican, Fikri (September 1970). "Surgical Grand Rounds from the University of Mississippi Medical Center". Southern Medical Journal. 63 (9): 1021–1029. doi:10.1097/00007611-197009000-00009. ISSN 0038-4348. PMID 5460095.
1970 Alican, Fikri; Çayırlı, Mukadder; Keith, Virginia (November 1970). "Fibrinolytic Activity Following Experimental Procedures on the Liver". Archives of Surgery. 101 (5): 590–595. doi:10.1001/archsurg.1970.01340290046010. ISSN 0004-0010. PMID 4920972.
1970 Hardy, James D.; Alican, Fikri; Moynihan, Patricia C.; Timmis, Hilary H.; Chavez, Carlos M.; Davis, J. T. Jr.; Anas, Pandeli (September 1970). "A Case of Clinical Lung Allotransplantation". The Journal of Thoracic and Cardiovascular Surgery. 60 (3): 411–426. doi:10.1016/S0022-5223(19)42353-2. ISSN 0022-5223. PMID 4916119.
1970 Şaşmaz, Orhan; Petridis, Ispiro; Alican, Fikri (January 1970). "Hematoma of the Rectus Abdominis Muscle". Archives of Surgery. 100 (1): 8–10. doi:10.1001/archsurg.1970.01340190010004. ISSN 0004-0010. PMID 5409682.
1970 Turner, Manson Don; Alican, Fikri (January–February 1970). "Successful 20-Hour Storage of the Canine Liver by Continuous Hypothermic Perfusion". Cryobiology. 6 (4): 293–301. doi:10.1016/s0011-2240(70)80083-9. ISSN 0011-2240. PMID 4911453.
1971 Alican, Fikri; Hardy, James D.; Çayırlı, Mukadder; Varner, Joseph E.; Moynihan, Patricia C.; Turner, Manson Don; Anas, Pandeli (February 1971). "Intestinal Transplantation: Laboratory Experience and Report of a Clinical Case". The American Journal of Surgery. 121 (2): 150–159. doi:10.1016/0002-9610(71)90092-4. ISSN 0002-9610. PMID 5540665.
1971 Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (22 February 1971). "One-Stage Replantation of Both Lungs in the Dog". JAMA. 215 (8): 1301–1306. doi:10.1001/jama.1971.03180210047009. ISSN 0098-7484. PMID 4929698.
1971 Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (March 1971). "Feasibility of Simultaneous Bilateral Lung Replantation". Transplantation Proceedings. 3 (1): 524–526. ISSN 0041-1345. PMID 4937931.
1971 Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (June 1971). "Surgical Technique of One-Stage Bilateral Lung Reimplantation in the Dog". The Journal of Thoracic and Cardiovascular Surgery. 61 (6): 847–856. doi:10.1016/S0022-5223(19)42146-6. ISSN 0022-5223. PMID 4932558.
1971 Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (July 1971). "Left Lung Replantation with Immediate Right Pulmonary Artery Ligation". Annals of Surgery. 174 (1): 34–43. doi:10.1097/00000658-197107010-00006. ISSN 0003-4932. PMC 1397426. PMID 4933526.
1971 Alican, Fikri; Çayırlı, Mukadder; Keith, Virginia (March 1971). "One-Stage Hepatectomy in the Dog with Restoration of the Vena Cava by End-to-End Anastomosis". Surgery. 69 (3): 427–432. ISSN 0039-6060. PMID 5544895.
1973 Alican, Fikri; Işın, Erol; Cockrell, John V. (February 1973). "One-Stage Allotransplantation of Both Lungs in the Dog". Annals of Surgery. 177 (2): 193–198. doi:10.1097/00000658-197302000-00012. ISSN 0003-4932. PMC 1355563. PMID 4572784.

Notes[edit]

  1. ^ Alican's official record of birth, 2 April 1930, is off by one year, a relatively common practice at the time by Turkish families hoping to secure, through late declaration of male births, an extra year of growth for their sons prior to conscription (formally at age eighteen).
  2. ^ Biographical details are available in Alican's autobiography (2000/2007), cited below in the references and listed above among his publications.[1]
  3. ^ The world's first heart transplant into a human was performed by James D. Hardy at the University of Mississippi Medical Center on 23 January 1964. The heart was that of a chimpanzee. As further progress in the United States awaited the resolution of ethical and legal issues in organ transplantation, other countries picked up the pace, and Christiaan Barnard became the first to use a human heart for the procedure, performing the operation in his native South Africa on 3 December 1967.[4]
  4. ^ His autobiography places the duration at twenty-five years. That figure originates in the first edition (2000), never updated in the second edition (2007).[45] The preface to his Genel Cerrahi (2007) gives the current figure as "more than thirty years."[46]
  5. ^ The combined page count of Alican's medical monographs (close to 5,000 pages) actually exceeds his own estimate of 3,000 pages[47] by more than 60%, which shows that the total he reports is a net figure excluding the 2007 compilation in order to avoid redundancy.
  6. ^ Alican, in his autobiography, identifies this volume (1968) as his first book, adding that he failed to attract attention (from publishers) to it for eight years between its completion in 1960 and its eventual publication in 1968.[48] This suggests that the first two entries listed among his monographs in the corresponding section above may, especially since the two titles are almost identical, at least in meaning, actually refer to the same work, perhaps the first (1960) being a printed manuscript and the second (1960) a proper publication. As against this possibility, the autobiography (2007) comes with a picture of the cover page of the first book (1960), where a publisher is in fact listed, along with a book series and the number of the specific title in that series.[49]
  7. ^ Alican's preface to Genel Cerrahi (2007), appearing in both volumes, introduces the entirety of that work as a compilation of previously published monographs with minor emendations. His tally in the preface is eleven books, counting as separate works both of the two editions of his study on cancer (1993/1997) as well as each volume of his trilogy on surgery (1994–1995), all listed above in the section on his publications.[50]

References[edit]

  1. ^ Jump up to: a b Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. ISBN 978-9-7542-0574-9.
  2. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 271–293. ISBN 978-9-7542-0574-9.
  3. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 312–313. ISBN 978-9-7542-0574-9.
  4. ^ Jump up to: a b "Dr. James D. Hardy". University of Mississippi Medical Center. Archived from the original on 2017-06-28. Retrieved 2016-06-29.
  5. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 312–313, 593–594. ISBN 978-9-7542-0574-9.
  6. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 228, 316–318, 319–320, 347–348, 389. ISBN 978-9-7542-0574-9.
  7. ^ Hardy, James D. (1986). The World of Surgery, 1945–1985: Memoirs of One Participant. Philadelphia: University of Pennsylvania Press. p. 290. ISBN 978-0-8122-8000-5.
  8. ^ Hardy, James D. (2002). The Academic Surgeon: An Autobiography. Mobile: Magnolia Mansions Press. pp. 223, 307. ISBN 978-0-9665-1755-2.
  9. ^ Alican, Fikri; Hardy, James D. (9 March 1963). "Lung Reimplantation: Effect on Respiratory Pattern and Function". JAMA. 183 (10): 849–853. doi:10.1001/jama.1963.63700100001013. ISSN 0098-7484. PMID 14012020.
  10. ^ Hardy, James D.; Eraslan, Şadan; Dalton, Jr., Martin L.; Alican, Fikri; Turner, Manson Don (May 1963). "Re-Implantation and Homotransplantation of the Lung: Laboratory Studies and Clinical Potential". Annals of Surgery. 157 (5): 707–718. doi:10.1097/00000658-196305000-00005. ISSN 0003-4932. PMC 1466537. PMID 13960767.
  11. ^ Hardy, James D.; Alican, Fikri (1966). "Lung Transplantation". Advances in Surgery. 2: 235–264. ISSN 0065-3411. PMID 5333296.
  12. ^ Alican, Fikri; Hardy, James D. (June 1967). "Eksperimantal Akciğer Transplantasyonu: Teknik, Fizyolojik ve İmmünolojik Problemler [Experimental Lung Transplantation: Technical, Physiological and Immunological Problems]". Türk Tıp Cemiyeti Mecmuası. 33 (6): 319–329. ISSN 0494-2736. PMID 4865363.
  13. ^ Hardy, James D.; Alican, Fikri; Moynihan, Patricia C.; Timmis, Hilary H.; Chavez, Carlos M.; Davis, J. T. Jr.; Anas, Pandeli (September 1970). "A Case of Clinical Lung Allotransplantation". The Journal of Thoracic and Cardiovascular Surgery. 60 (3): 411–426. doi:10.1016/S0022-5223(19)42353-2. ISSN 0022-5223. PMID 4916119.
  14. ^ Alican, Fikri (December 1970). "The Present Status of Lung Transplantation". Journal of the Tennessee Medical Association [later: Tennessee Medicine]. 63 (12): 1011–1021. ISSN 0040-3318. PMID 5532334.
  15. ^ Jump up to: a b Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (22 February 1971). "One-Stage Replantation of Both Lungs in the Dog". JAMA. 215 (8): 1301–1306. doi:10.1001/jama.1971.03180210047009. ISSN 0098-7484. PMID 4929698.
  16. ^ Jump up to: a b Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (March 1971). "Feasibility of Simultaneous Bilateral Lung Replantation". Transplantation Proceedings. 3 (1): 524–526. ISSN 0041-1345. PMID 4937931.
  17. ^ Jump up to: a b Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (June 1971). "Surgical Technique of One-Stage Bilateral Lung Reimplantation in the Dog". The Journal of Thoracic and Cardiovascular Surgery. 61 (6): 847–856. doi:10.1016/S0022-5223(19)42146-6. ISSN 0022-5223. PMID 4932558.
  18. ^ Jump up to: a b Alican, Fikri; Çayırlı, Mukadder; Işın, Erol; Hardy, James D. (July 1971). "Left Lung Replantation with Immediate Right Pulmonary Artery Ligation". Annals of Surgery. 174 (1): 34–43. doi:10.1097/00000658-197107010-00006. ISSN 0003-4932. PMC 1397426. PMID 4933526.
  19. ^ Jump up to: a b Alican, Fikri; Işın, Erol; Cockrell, John V. (February 1973). "One-Stage Allotransplantation of Both Lungs in the Dog". Annals of Surgery. 177 (2): 193–198. doi:10.1097/00000658-197302000-00012. ISSN 0003-4932. PMC 1355563. PMID 4572784.
  20. ^ Alican, Fikri (1967). "Experimental Orthotopic Liver Transplantation: Experience with 150 Dogs". New Istanbul Contribution to Clinical Science. 9 (3): 71–98. ISSN 0028-5447. PMID 16300153.
  21. ^ Alican, Fikri (April 1967). "Köpekte Total Hepatektomiden Sonra Karaciğerin Tekrar Yerine Takılması [Replantation of the Liver in Dogs Following Total Hepatectomy]". Türk Tıp Cemiyeti Mecmuası. 33 (4): 209–226. ISSN 0494-2736. PMID 4863470.
  22. ^ Alican, Fikri (May 1967). "Eksperimantal Karaciğer Homotransplantasyonu [Experimental Liver Homotransplantation]". Türk Tıp Cemiyeti Mecmuası. 33 (5): 296–311. ISSN 0494-2736.
  23. ^ Alican, Fikri; Hardy, James D. (August 1967). "Replantation of the Liver in Dogs". The Journal of Surgical Research. 7 (8): 368–375. doi:10.1016/0022-4804(67)90080-7. ISSN 0022-4804.
  24. ^ Alican, Fikri; Hardy, James D. (1969). "A Description of the Course of Long-Term Survivors of Dog Liver Replantation". Surgical Forum. 20: 365–367. ISSN 0071-8041. PMID 4910609.
  25. ^ Turner, Manson Don; Alican, Fikri (January–February 1970). "Successful 20-Hour Storage of the Canine Liver by Continuous Hypothermic Perfusion". Cryobiology. 6 (4): 293–301. doi:10.1016/s0011-2240(70)80083-9. ISSN 0011-2240. PMID 4911453.
  26. ^ Alican, Fikri; Çayırlı, Mukadder; Keith, Virginia (November 1970). "Fibrinolytic Activity Following Experimental Procedures on the Liver". Archives of Surgery. 101 (5): 590–595. doi:10.1001/archsurg.1970.01340290046010. ISSN 0004-0010. PMID 4920972.
  27. ^ Alican, Fikri; Çayırlı, Mukadder; Keith, Virginia (March 1971). "One-Stage Hepatectomy in the Dog with Restoration of the Vena Cava by End-to-End Anastomosis". Surgery. 69 (3): 427–432. ISSN 0039-6060. PMID 5544895.
  28. ^ Alican, Fikri; Hardy, James D.; Çayırlı, Mukadder; Varner, Joseph E.; Moynihan, Patricia C.; Turner, Manson Don; Anas, Pandeli (February 1971). "Intestinal Transplantation: Laboratory Experience and Report of a Clinical Case". The American Journal of Surgery. 121 (2): 150–159. doi:10.1016/0002-9610(71)90092-4. ISSN 0002-9610. PMID 5540665.
  29. ^ Alican, Fikri; Hardy, James D. (1961). "Relationship and Significance of the Levels of Direct Bilirubin, Indirect Bilirubin, and Alkaline Phosphatase in Lymph, Blood, and Urine After Ligation of the Common Bile Duct". Surgical Forum. 12: 337–339. ISSN 0071-8041. PMID 13860424.
  30. ^ Hardy, James D.; Alican, Fikri (July 1961). "Ischemic Gangrene without Major Organic Vascular Occlusion: An Enlarging Concept". Surgery. 50 (1): 107–114. ISSN 0039-6060. PMID 13711520.
  31. ^ Alican, Fikri (March 1962). "A Sensitive Method for Recording Lymph Flow: Observations on the Dynamics of Hepatosplanchnic Blood and Lymph". The Journal of Surgical Research. 2 (2): 104–109. doi:10.1016/S0022-4804(62)80004-3. ISSN 0022-4804. PMID 13860425.
  32. ^ Alican, Fikri; Hardy, James D. (August 1962). "Lymphatic Transport of Bile Pigments and Alkaline Phosphatase in Experimental Common Duct Obstruction". Surgery. 52 (2): 366–372. ISSN 0039-6060. PMID 13860422.
  33. ^ Şaşmaz, Orhan; Petridis, Ispiro; Alican, Fikri (January 1970). "Hematoma of the Rectus Abdominis Muscle". Archives of Surgery. 100 (1): 8–10. doi:10.1001/archsurg.1970.01340190010004. ISSN 0004-0010. PMID 5409682.
  34. ^ Alican, Fikri (1968). Transplantasyon Biyolojisi: Hızla Gelişmekte Olan Yeni Bir Bilim [Transplantation Biology: A Rapidly Developing New Science]. Istanbul: İstanbul Üniversitesi Tıp Fakültesi.
  35. ^ Alican, Fikri; Hardy, James D. (December 1961). "Mechanisms of Shock as Reflected in Studies of Lymph of Abdominal Organs". Surgery, Gynecology & Obstetrics [later: Journal of the American College of Surgeons]. 113: 743–756. ISSN 0039-6087. PMID 13860423.
  36. ^ Alican, Fikri (August 1962). "Pathophysiology of Endotoxin Shock: Clinical Observations and Experimental Studies". The American Journal of the Medical Sciences. 244 (2): 237–257. doi:10.1097/00000441-196208000-00014. ISSN 0002-9629. PMID 13860426.
  37. ^ Alican, Fikri; Hardy, James D. (1962). "Sympatho-Adrenal System in Endotoxin Shock". Surgical Forum. 13: 8–10. ISSN 0071-8041. PMID 14012021.
  38. ^ Alican, Fikri; Dalton, Jr., Martin L.; Hardy, James D. (June 1962). "Experimental Endotoxin Shock: Circulatory Changes with Emphasis upon Cardiac Function". The American Journal of Surgery. 103 (6): 702–708. doi:10.1016/0002-9610(62)90249-0. ISSN 0002-9610. PMID 13860421.
  39. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 493–496. ISBN 978-9-7542-0574-9.
  40. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 385–390, 418–420. ISBN 978-9-7542-0574-9.
  41. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 428–431, 457–458. ISBN 978-9-7542-0574-9.
  42. ^ "James D. Hardy Society". University of Mississippi Medical Center. Retrieved 2016-06-29.[permanent dead link]
  43. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 492–493. ISBN 978-9-7542-0574-9.
  44. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 573–576. ISBN 978-9-7542-0574-9.
  45. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. p. 573. ISBN 978-9-7542-0574-9. See pp. 574–575 for an itemized list of the twenty-two journals.
  46. ^ Alican, Fikri (2007). Genel Cerrahi [General Surgery]. Vol. one. Istanbul: Nobel Tıp Kitabevleri. p. vi. ISBN 978-9-7542-0532-9. Reprinted in volume two (pp. vi) ISBN 978-9-7542-0533-6.
  47. ^ Jump up to: a b Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. p. 576. ISBN 978-9-7542-0574-9.
  48. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. pp. 288–290, 380. ISBN 978-9-7542-0574-9.
  49. ^ Alican, Fikri (2007) [1st ed. 2000]. Koca Meşe'nin Gölgesi [The Shadow of the Grand Oak] (2nd ed.). Istanbul: Nobel Tıp Kitabevleri. p. 289. ISBN 978-9-7542-0574-9.
  50. ^ Alican, Fikri (2007). Genel Cerrahi [General Surgery]. Vol. one. Istanbul: Nobel Tıp Kitabevleri. pp. vi–vii. ISBN 978-9-7542-0532-9. Reprinted in volume two (pp. vi-vii) ISBN 978-9-7542-0533-6.

Gallery[edit]

  • Fikri Alican (age 26) in May 1955 at graduation from medical school (Istanbul University)
    Fikri Alican (age 26) in May 1955 at graduation from medical school (Istanbul University)
  • Fikri Alican (age 26) in May 1955 as a young doctor fresh out of medical school (Istanbul University)
    Fikri Alican (age 26) in May 1955 as a young doctor fresh out of medical school (Istanbul University)
  • Fikri Alican (age 31) in the summer of 1960 visiting his parents at their home
    Fikri Alican (age 31) in the summer of 1960 visiting his parents at their home
  • Fikri Alican (age 40) in July 1969 at a conference on organ transplantation in Madrid
    Fikri Alican (age 40) in July 1969 at a conference on organ transplantation in Madrid
  • Fikri Alican (age early 40s) in the early 1970s delivering a lecture at Istanbul University
    Fikri Alican (age early 40s) in the early 1970s delivering a lecture at Istanbul University
  • Fikri Alican (age 76) in August 2005 at home
    Fikri Alican (age 76) in August 2005 at home
  • Fikri Alican (age 77) in August 2006 at home
    Fikri Alican (age 77) in August 2006 at home
  • Fikri Alican (age 77) in December 2006 at his office
    Fikri Alican (age 77) in December 2006 at his office
  • Fikri Alican (age 78) in June 2007 at home
    Fikri Alican (age 78) in June 2007 at home
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