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Indobufen

From Wikipedia, the free encyclopedia
Indobufen
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.058.496 Edit this at Wikidata
Chemical and physical data
FormulaC18H17NO3
Molar mass295.338 g·mol−1
3D model (JSmol)
  • O=C(O)C(c1ccc(cc1)N3C(=O)c2ccccc2C3)CC
  • InChI=1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22) ☒N
  • Key:AYDXAULLCROVIT-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Indobufen is a platelet aggregation inhibitor.[1] It acts as a reversible cyclooxygenase inhibitor.[2]

References

[edit]
  1. ^ The Merck Index (12th ed.). p. 4991.
  2. ^ Eligini S, Violi F, Banfi C, Barbieri SS, Brambilla M, Saliola M, et al. (January 2006). "Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism". Cardiovascular Research. 69 (1): 218–26. doi:10.1016/j.cardiores.2005.07.013. PMID 16154551.