Arne Astrup
Арне Вернон Астроп | |
|---|---|
| Рожденный | 1 августа 1955 г. Фредериксберг , Дания |
| Национальность | Датский |
| Альма -матер | Университет Копенгагена |
| Научная карьера | |
| Поля | |
| Учреждения | Университет Копенгагена , Фонд Ново Нордиск |
Арне Вернон Астроп (родился 1 августа, в Фредериксберге , 1955) - датский диетолог , главный врач , исследователь , автор и профессор . Он известен как исследователь, коммуникатор и автор и опубликовал более 900 научных статей . [ 1 ] В 2018 году он был на международном уровне признан одним из самых цитируемых исследователей в мире. [ 2 ] Arne Astrup способствовал идентификации GLP-1 как гормона сытости, [ 3 ] который сыграл ключевую роль в разработке лекарств GLP-1 для лечения ожирения , [ 4 ] который способствовал успеху Ново Нордиск A/S и их наркотиков Wegovy . [ 5 ]
С 1990 по 2020 год был главой кафедры питания, упражнений и спорта на факультете наук в Университете Копенгагена . Осенью 2016 года департамент был оценен всемирно признанным Шанхайским рейтингом в качестве ведущей мировой исследовательской среды в своей области. [ 6 ]
Астроп завершил свое медицинское образование в Университете Копенгагена в 1981 году. В 1986 году он получил медицинскую докторскую степень (доктор Мед.) За диссертацию по метаболизму у людей. [ 7 ] Впоследствии он продолжил обучение в качестве специалиста по внутренней медицине . Он был на последнем этапе своего специализированного обучения, когда стал главой Датского Королевского ветеринарного и сельскохозяйственного университета в 1990 году. Он стал рыцарем Ордена Даннеброга в 1999 году королевой ее величества Маргрет II из Дании и рыцаря 1 -го класса Орден Даннеброга в 2012 году. [ 8 ]
С 1 июля 2020 года Arne Astrup взял на себя роль старшего вице -президента по ожирению и питательным наукам в Фонде Novo Nordisk . [ 2 ]
Карьера и признание
[ редактировать ]Arne Astrup достиг национального и международного признания с 1990 -х годов. Он известен тем, что является одним из самых цитируемых исследователей в мире. Его работа на пересечении между промышленностью и научными кругами привела к нескольким противоречиям [ 9 ] Это сделало его имя публично известным в более широком датском населении. [ 10 ]
Признание
[ редактировать ]- Внимание общественности: в 1990 -х годах Арне Астроп привлек внимание общественности благодаря своим новым методам измерения аппетита и потребления энергии.
- Председатель Национального совета по питанию: с 1993 по 2001 год он был председателем Национального совета по питанию (заменен Советом по физической активности и питанию в 2005 году) и внес свой вклад в запрет на транс -жиры промышленного производства в Дании в 2004 году. [ 8 ]
- Академически активная в течение 30 лет: в течение академической карьеры, охватывающей 30 лет, Arne Astrup в основном сосредоточился на исследованиях в области регуляции аппетита, лечении ожирения, диабета 2 типа , сердечно -сосудистых заболеваниях и других состояниях, где питание и физическая активность являются значительными.
- GLP-1 как гормон сытости: в 1996 году, вместе с Йенсом Юлом Холстом , он идентифицировал GLP-1 как гормон сытости, что привело к патенту, который помог novo Nordisk A/S разработать аналоги GLP-1 для тяжелого ожирения. [ 8 ]
- World Obesity Federation: Astrup was president of the World Obesity Federation for four years (formerly The International Association for the Study of Obesity (IASO)).[8][2]
- OPUS Centre: Director of the OPUS Centre ("New Nordic Everyday Food") supported by the Nordea Foundation with DKK 100 million (2009–2014).
- Obesity Reviews: Arne Astrup was the founding editor-in-chief of the English journal Obesity Reviews (from 1999 to 2010).[5][8]
- American Journal of Clinical Nutrition: Editor of the American Journal of Clinical Nutrition since 2010.[8][7]
- Shanghai Rankings: Under his leadership, the Department of Sports and Nutrition at the University of Copenhagen was recognised as the world's leading institution in sports research by the Shanghai Ranking in 2018.[8]
- 900+ scientific articles: He has published more than 900 peer-reviewed scientific articles and over 1000 other academic texts, including abstracts, textbook chapters, and scientific letters.[4][5]
- Among the world's most cited: Arne Astrup is internationally recognised as one of the world's most cited researchers.[8]
- Knight of the Order of the Dannebrog: Knight of the Order of the Dannebrog in 1999, and Knight 1st Class of the Order of the Dannebrog in 2012.
Arne Astrup's research
[edit]Arne Astrup has a background in nutrition research, where he has worked with both experimental physiological and biochemical research as well as clinical treatment trials with subjects and patients. His scientific work has contributed to the understanding of human appetite regulation and energy metabolism, which has led to insights into adipose tissue deposition and body weight.[11][5]
GLP-1 as a satiety hormone in humans
[edit]In collaboration with Professor Jens Juul Holst, he discovered that GLP-1 acts as a satiety hormone in humans.[3][5] This discovery has played a key role in the development of GLP-1 drugs for the treatment of obesity, which has contributed to the success of Novo Nordisk A/S and their drug Wegovy.
Arne Astrup has published numerous scientific articles in recognized international journals such as The Lancet, British Medical Journal, Nature[8] and New England Journal of Medicine. In 2018, he was included in the Web of Science list of the world's most cited scientists.[7]
Throughout his career, Astrup has also been a dedicated supervisor for 42 PhD students[5] and has contributed to research through an interdisciplinary perspective since his student days.
Activity
[edit]Despite being a department head for decades and hence not expected to be actively researching, Arne Astrup has published more than 900 scientific publications, as well as a number of scientific and popular science books throughout his career. As a result, in 2010 he was ranked number 5 in the international ranking of the world's most productive researchers in the field of overweight and obesity by ISIS Reuters. He is also a frequent contributor to leading medical journals such as The Lancet, New England Journal of Medicine and American Journal of Clinical Nutrition. Professionally, he is a trendsetter, which is why in 2018 he was included in Clarivate's exclusive list of the most cited researchers in the world.[5][7] A list that only 32 other researchers at the University of Copenhagen have made. He has also written columns and letters to the editor in Ekstra Bladet, 24 Timer and Ude og Hjemme, among others. He has received numerous honors for his research and was appointed Knight of Dannebrog in 1991 and Knight of the Order of Dannebrog 1st degree in 2012.
Through his work as head of the Department of Human Nutrition (and since 2012 the Department of Nutrition, Exercise and Sports), Arne Astrup has had a significant influence on the development of the field of nutrition, including being the initiator of establishing the Master's programs in Human Nutrition, as well as Clinical Nutrition at the Danish Royal Veterinary and Agricultural University (since 2007 part of the University of Copenhagen).
Arne Astrup is behind the EU diet project “Diogenes”,[12] supported by the EU Framework Program with 15 million euros, which showed that a diet with more protein and fewer carbohydrates could promote weight control in overweight people after weight loss. Together with Master of Science in Human Nutrition Christian Bitz, he has disseminated the principles of Diogenes in the book “The World's Best Diet”, which has sold over 100,000 copies and has been translated into 4 languages.
Criticism and Controversies
[edit]Astrup has faced criticism for combining his research responsibilities with personal economic interests on several occasions. For instance, he held a dual role with the company Neurosearch, acting as an advisor and owning stocks while publicly endorsing the company’s diet pill in his column, "Doktor Slank" ("Doctor Skinny").[13] This raised concerns about potential conflicts of interest. Following the negative publicity, Astrup sold his shares in Neurosearch, which were valued at approximately DKK 200,000.[13] He maintains that he was able to keep his professional and personal interests separate.
Awards and Honours
[edit]Arne Astrup has received a number of Danish and international awards throughout his career, including:
| Year | Award |
|---|---|
| 1990 | Danish Obesity Research Award |
| 1990 | Servier’s Award for Outstanding Obesity Research[14][15] |
| 1994 | IASO Andrew Mayer Award[15] |
| 1995 | Mölnlycke Life Quality Award |
| 2002 | Danone Chair in Nutrition 2002 at The University of Antwerp[14] |
| 2007 | University of Copenhagen: Communications Award[16] |
| 2009 | International Association of Business Communicators’ EME Excel Merit Award for Communication Leadership[14] |
| 2010 | University of Copenhagen: Innovation Award[17] |
| 2010 | Nutrition & Santé Weight Management Award (France)[14] |
| 2012 | Finnish Association of Internal Medicine Esko Nikkilä Prize[18] |
| 2012 | American Society for Nutrition Robert H. Herman Award[19][20] |
| 2012 | Danish Communication Association KomPris´12 to the OPUS Research Centre[14] |
| 2014 | IASO Willendorf Award[5] |
Authorship
[edit]Arne Astrup has published several books together with other authors such as Claus Meyer, Christian Bitz, Mads Fiil Hjorth and others.[21]
| Year | Title | Akuthors |
|---|---|---|
| 2018 | Type C - Spis dig slank efter Blodsukkerkuren | Arne Astrup, Christian Bitz, Mads Fiil Hjorth |
| 2017 | Spis dig slank efter dit blodsukker | Arne Astrup, Christian Bitz |
| 2017 | Type A - spis dig slank efter dit blodsukker | Arne Astrup, Christian Bitz, Mads Fiil Hjorth |
| 2017 | Type B - spis dig slank efter dit blodsukker | Arne Astrup, Christian Bitz, Mads Fiil Hjorth |
| 2017 | Type A - spis dig slank efter dit blodsukker | Arne Astrup, Christian Bitz, Mads Fiil Hjorth |
| 2017 | The Nordic Way | Jennie Brand-Miller, Arne Astrup, Christian Bitz |
| 2016 | Til Øllet | Arne Astrup, Erik Skovenborg |
| 2015 | Rigtig Mad | Arne Astrup, Thilde Jo Maarbjerg, Thomas Rode Andersen |
| 2014 | Verdens sundeste mor og barn | Arne Astrup, Christian Bitz |
| 2012 | Verdens Bedste Kur | Arne Astrup, Christian Bitz |
| 2012 | Verdens bedste kur vol. 2.0 | Arne Astrup, Christian Bitz |
| 2007 | Spis Igennem | Arne Astrup, Claus Meyer |
| 2004 | 100 spørgsmål til professoren - og 100 svar. Slankeguiden 2004 | Arne Astrup |
References
[edit]- ^ "Arne Astrup". scholar.google.com. Retrieved 2024-07-30.
- ^ Jump up to: a b c "Professor Arne Astrup to head ambitious initiative promoting healthy weight among children". Novo Nordisk Fonden. Retrieved 2024-07-30.
- ^ Jump up to: a b Astrup, Arne (July 2024). "Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions". European Journal of Clinical Nutrition. 78 (7): 551–556. doi:10.1038/s41430-024-01460-6. ISSN 1476-5640. PMC 11230893. PMID 38890501.
- ^ Jump up to: a b Astrup, Arne (July 2024). "Reflections on the discovery GLP-1 as a satiety hormone: Implications for obesity therapy and future directions". European Journal of Clinical Nutrition. 78 (7): 551–556. doi:10.1038/s41430-024-01460-6. ISSN 1476-5640. PMC 11230893. PMID 38890501.
- ^ Jump up to: a b c d e f g h Swiss RE - Arne Astrup: https://www.swissre.com/profile/Arne_Astrup/ep_3b340a
- ^ Madsen, Kristian Levring (2023-10-18). "The University of Copenhagen is among the world's best research environments in Sport Science". nexs.ku.dk. Retrieved 2024-07-30.
- ^ Jump up to: a b c d American Journal of Nutrition: Meet the AJCN Editorial Board - https://ajcn.nutrition.org/editorialboard
- ^ Jump up to: a b c d e f g h i "Editorial Board | European Journal of Clinical Nutrition". www.nature.com. Retrieved 2024-07-30.
- ^ AJCN Nutrion: Conflict of Interest Statements for AJCN Editors - https://ajcn.nutrition.org/content/conflict-of-interest-statements
- ^ FROM_OLD_SITE, MIGRATED_ARTICLES (2009-07-28). "Weight loss hero or sweet-toothed villain?". University Post – Independent of management (in Danish). Retrieved 2024-07-30.
- ^ "Arne Astrup". www.arlafoodsingredients.com. Retrieved 2024-07-30.
- ^ Papadaki, Angeliki; Linardakis, Manolis; Plada, Maria; Larsen, Thomas M.; van Baak, Marleen A.; Lindroos, Anna Karin; Pfeiffer, Andreas F. H.; Martinez, J. Alfredo; Handjieva-Darlenska, Teodora; Kunešová, Marie; Holst, Claus; Saris, Wim H. M.; Astrup, Arne; Kafatos, Anthony; Diet, Obesity and Genes (DiOGenes) Project (2013). "A multicentre weight loss study using a low-calorie diet over 8 weeks: regional differences in efficacy across eight European cities". Swiss Medical Weekly. 143: w13721. doi:10.4414/smw.2013.13721. hdl:10171/28173. ISSN 1424-3997. PMID 23348658.
- ^ Jump up to: a b Baggersgaard, Claus (2009-07-28). "Weight loss hero or sweet-toothed villain?". University Post – Independent of management (in Danish). Retrieved 2024-08-03.
- ^ Jump up to: a b c d e Milknutritiousbynature.com: Symposia, September 2014 - http://www.milknutritiousbynature.eu/fileadmin/milk/Document_Library/RS14_Biographies.pdf
- ^ Jump up to: a b "Obesity Clinician, Arne Astrup, former President of the International Association for the Study of Obesity, joins Gelesis Advisory Board". Retrieved 2024-08-03.
- ^ Sundhed, Center for Holdspil og (2012-12-06). "Tilknyttede medarbejdere". holdspil.ku.dk (in Danish). Retrieved 2024-08-03.
- ^ Ernæring, Institut for Idræt og (2012-10-09). "Ansatte". nexs.ku.dk (in Danish). Retrieved 2024-08-03.
- ^ Nutrition, Exercise and Sports (2012-10-09). "Staff". nexs.ku.dk. Retrieved 2024-08-03.
- ^ American Society for Nutrition Awards Recipients: https://nutrition.org/wp-content/uploads/2017/08/American-Society-for-Nutrition-Awards_Prior-Recipients.pdf
- ^ Ernæring, Institut for Idræt og (2012-10-09). "Ansatte". nexs.ku.dk (in Danish). Retrieved 2024-08-03.
- ^ "Books by Arne Astrup (Author of The Nordic Way)". www.goodreads.com. Retrieved 2024-08-03.