Cancer susceptibility 1

DNAI7
Identifiers
Aliases	DNAI7, LAS1, PPP1R54, cancer susceptibility candidate 1, cancer susceptibility 1, cilia and flagella associated protein 94, CASC1, dynein axonemal intermediate chain 7, CFAP94
External IDs	OMIM: 616906; MGI: 2444480; HomoloGene: 41242; GeneCards: DNAI7; OMA:DNAI7 - orthologs
showGene location (Human)
Chr.	Chromosome 12 (human)
End	25,195,162 bp
showGene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	145,156,731 bp
showRNA expression pattern
	Top expressed in
	sperm; ; bronchial epithelial cell; ; right uterine tube; ; olfactory zone of nasal mucosa; ; testicle; ; buccal mucosa cell; ; mucosa of paranasal sinus; ; left testis; ; right testis; ; Epithelium of choroid plexus;
	Top expressed in
	zygote; ; secondary oocyte; ; primary oocyte; ; spermatid; ; spermatocyte; ; testicle; ; ovary; ; hypothalamus; ; granulocyte; ; embryo;
	More reference expression data
	n/a
hideOrthologs
	55259
	320662
	ENSG00000118307
	ENSMUSG00000043541
	Q6TDU7
	Q6TDU8
showNM_001082972 ; NM_001082973 ; NM_001204101 ; NM_001204102 ; NM_018272 ;
	NM_001319977; NM_001319978; NM_001352061; NM_001352062; NM_001352063; NM_001352064; NM_001352065; NM_001352066; NM_001352067; NM_001352068
	NM_177222
showNP_001076441 ; NP_001076442 ; NP_001191030 ; NP_001191031 ; NP_001306906 ;
	NP_001306907; NP_060742; NP_001338990; NP_001338991; NP_001338992; NP_001338993; NP_001338994; NP_001338995; NP_001338996; NP_001338997
	NP_796196
	Викидид
Посмотреть/редактировать человека	Посмотреть/редактировать мышь

Casc1, alias Las1, is one of the six genes constituting the mouse Pulmonary adenoma susceptibility 1 (Pas1) locus haplotype.^[5] Cancer susceptibility 1 is a protein that in humans is encoded by the CASC1 gene. ^[6]

References

^ Jump up to: ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118307 – Ensembl, May 2017
^ Jump up to: ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043541 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Manenti G, Galbiati F, Giannì-Barrera R, Pettinicchio A, Acevedo A, Dragani TA. Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice. Oncogene. 2004;23(25):4495–4504.
^ «Ген Entrez: восприимчивость к раку 1» . Получено 2018-07-16 .

Дальнейшее чтение

Manenti G, Galbiati F, Pettinicchio A, Spinola M, Piconese S, Leoni VP, B, Ravagnani F, Investment M, Pastorino U, Dragani TA (июль 2006 г.). «Полиморфизм V141L гена LMP человека связан с выживанием больного раком легких» . Канцерогенез . 27 (7): 1386–90. Doi : 10.1093/crigin/bgi332 . PMID 16410263 .
Кохо Т., Кунито Х., Сузуки К., Ямамото С., Кучиба А., Мацуно Ю., Янагитани Н., Йокота Дж (май 2008). «Ассоциация полиморфизмов KRAS с риском аденокарциномы легких сопровождается атипичной аденоматозной гиперплазией» . Канцерогенез . 29 (5): 957–63. doi : 10.1093/carcin/bgn048 . PMID 18299280 .
Eijineheim M, Newton-Cheh C, Sotoodehnia N, The Baker Pi, Müller M, Morrison AC, Smith A, Sanna S, Sanna S, Navarro P, Navorro P, Nuttrada K, EJ, EJ, ET, Highter SJ, Bis JC, Rückert IM, Alonso A, Launer LJ, Hottenga JJ, Rivadenera F, Noseworthy PA, Rice KM, Perz S, Arking TD, Aulchenko YS, Tarasov KV, Tarasov KV, Wild SH, Marroni F, Gift C, Light Cm, CM , Prineas RJ, Courtman A, Rotter Ji, Hicks AA, Ernst F, Njjar SS, Wright A, Fox ER, Oestar HK, Couper D, Voelzke H, Campbell H, Campbell H, Campbell H, Campbell H, Campbell H, Campbell H, H., Бешенник T, Uda M, Whiteman JC, Psty BM, Forris TB, Harris TB, CEA CM, Lakatta EC, Felix SB, Gudnason V, Pfeufer A, Heckbert SR, Sticker BH, Board E, O'Donnell CJ (октябрь 2010 г.). «Анализ ассоциации по всему геномии идентично L локусы, связанные с местом жительства сердец» . Гул Крот. Gnet . 19 (19): 3885–94. doi : 10,1093/hmg/ddq303 Полем PMC 3657480 . PMID 20639392 .

Эта статья о гене о хромосоме человека 12 является заглушкой . Вы можете помочь Википедии, расширив ее .

[refGRCh38Ensembl-1] Jump up to: ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000118307 – Ensembl, May 2017

[refGRCm38Ensembl-2] Jump up to: ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000043541 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[5] Manenti G, Galbiati F, Giannì-Barrera R, Pettinicchio A, Acevedo A, Dragani TA. Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice. Oncogene. 2004;23(25):4495–4504.

[entrez-6] «Ген Entrez: восприимчивость к раку 1» . Получено 2018-07-16 .

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