2-метилиндола

2-метилиндола
Имена
	Предпочтительное имя IUPAC 2-метил-1 H -индоль
Идентификаторы
Номер CAS	95-20-5 ;
3D model ( JSmol )	Интерактивное изображение ;
ChEMBL	ChEMBL259419 ;
ChemSpider	6954 ;
ECHA InfoCard	100.002.181
PubChem CID	7224;
UNII	I7CN58827I ;
CompTox Dashboard (EPA)	DTXSID5059117 ;
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Properties
Chemical formula	C9H9N
Molar mass	131.178 g·mol−1
Appearance	Yellow viscous liquid
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Метилкетол или 2-метилиндол представляет собой мягко токсичное и слегка легковоспламеняющееся органическое соединение , которое происходит в виде белого твердого вещества, которое с течением времени становится коричневым. ^{[ 1 ]}^{[ 2 ]} У него химическая формула C ₉ H ₉ н . ^{[ 3 ]}

Метилкетол используется в качестве промежуточного соединения для синтеза красителей , ^{[ 4 ]} пигменты , ^{[ 5 ]} Оптические ярлыки и фармацевтические препараты . ^{[ 6 ]}

Смотрите также

Ссылки

^ Brown, Daniel R.; Clark, Bryan W.; Garner, Lindsey V. T.; Di Giulio, Richard T. (June 2015). "Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists". Environmental Science and Pollution Research International. 22 (11): 8329–8338. Bibcode:2015ESPR...22.8329B. doi:10.1007/s11356-014-3969-2. ISSN 1614-7499. PMC 4442063. PMID 25532870.
^ Brown, D. R.; Clark, B. W.; Garner, L. V. T.; Di Giulio, R. T. (October 2016). "Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)". Comparative Biochemistry and Physiology. Toxicology & Pharmacology. 188: 45–51. doi:10.1016/j.cbpc.2016.05.005. ISSN 1532-0456. PMID 27211013.
^ Parker, Amie; Lamata, Pilar; Viguri, Fernando; Rodríguez, Ricardo; López, José A.; Lahoz, Fernando J.; García-Orduña, Pilar; Carmona, Daniel (2020-10-12). "Half-sandwich complexes of osmium containing guanidine-derived ligands". Dalton Transactions. 49 (39): 13601–13617. doi:10.1039/d0dt02713h. hdl:10261/233133. ISSN 1477-9234. PMID 32975256. S2CID 221913494.
^ Casas-Catalán, María José; Doménech-Carbó, María Teresa (May 2005). "Identification of natural dyes used in works of art by pyrolysis-gas chromatography/mass spectrometry combined with in situ trimethylsilylation". Analytical and Bioanalytical Chemistry. 382 (2): 259–268. doi:10.1007/s00216-005-3064-0. ISSN 1618-2642. PMID 15782338. S2CID 44407380.
^ Shaki, Hanieh; Gharanjig, Kamaladin; Khosravi, Alireza (July 2015). "Synthesis and investigation of antimicrobial activity and spectrophotometric and dyeing properties of some novel azo disperse dyes based on naphthalimides". Biotechnology Progress. 31 (4): 1086–1095. doi:10.1002/btpr.2107. ISSN 1520-6033. PMID 25967675. S2CID 25349059.
^ Ozcan-Sezer, Senem; Ince, Elif; Akdemir, Atilla; Ceylan, Özlem Öztürk; Suzen, Sibel; Gurer-Orhan, Hande (May 2019). "Aromatase inhibition by 2-methyl indole hydrazone derivatives evaluated via molecular docking and in vitro activity studies". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 49 (5): 549–556. doi:10.1080/00498254.2018.1482029. ISSN 1366-5928. PMID 29804490. S2CID 44062839.

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[1] Brown, Daniel R.; Clark, Bryan W.; Garner, Lindsey V. T.; Di Giulio, Richard T. (June 2015). "Zebrafish cardiotoxicity: the effects of CYP1A inhibition and AHR2 knockdown following exposure to weak aryl hydrocarbon receptor agonists". Environmental Science and Pollution Research International. 22 (11): 8329–8338. Bibcode:2015ESPR...22.8329B. doi:10.1007/s11356-014-3969-2. ISSN 1614-7499. PMC 4442063. PMID 25532870.

[2] Brown, D. R.; Clark, B. W.; Garner, L. V. T.; Di Giulio, R. T. (October 2016). "Embryonic cardiotoxicity of weak aryl hydrocarbon receptor agonists and CYP1A inhibitor fluoranthene in the Atlantic killifish (Fundulus heteroclitus)". Comparative Biochemistry and Physiology. Toxicology & Pharmacology. 188: 45–51. doi:10.1016/j.cbpc.2016.05.005. ISSN 1532-0456. PMID 27211013.

[3] Parker, Amie; Lamata, Pilar; Viguri, Fernando; Rodríguez, Ricardo; López, José A.; Lahoz, Fernando J.; García-Orduña, Pilar; Carmona, Daniel (2020-10-12). "Half-sandwich complexes of osmium containing guanidine-derived ligands". Dalton Transactions. 49 (39): 13601–13617. doi:10.1039/d0dt02713h. hdl:10261/233133. ISSN 1477-9234. PMID 32975256. S2CID 221913494.

[4] Casas-Catalán, María José; Doménech-Carbó, María Teresa (May 2005). "Identification of natural dyes used in works of art by pyrolysis-gas chromatography/mass spectrometry combined with in situ trimethylsilylation". Analytical and Bioanalytical Chemistry. 382 (2): 259–268. doi:10.1007/s00216-005-3064-0. ISSN 1618-2642. PMID 15782338. S2CID 44407380.

[5] Shaki, Hanieh; Gharanjig, Kamaladin; Khosravi, Alireza (July 2015). "Synthesis and investigation of antimicrobial activity and spectrophotometric and dyeing properties of some novel azo disperse dyes based on naphthalimides". Biotechnology Progress. 31 (4): 1086–1095. doi:10.1002/btpr.2107. ISSN 1520-6033. PMID 25967675. S2CID 25349059.

[6] Ozcan-Sezer, Senem; Ince, Elif; Akdemir, Atilla; Ceylan, Özlem Öztürk; Suzen, Sibel; Gurer-Orhan, Hande (May 2019). "Aromatase inhibition by 2-methyl indole hydrazone derivatives evaluated via molecular docking and in vitro activity studies". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 49 (5): 549–556. doi:10.1080/00498254.2018.1482029. ISSN 1366-5928. PMID 29804490. S2CID 44062839.

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